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Phospho-BRAF (S445) Antibody

CAT: 0013-GTR18329179-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0013-GTR18329179-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Affinity Purified Rabbit Polyclonal Antibody (Pab)
Product Name Alternative
Serine/threonine-protein kinase B-raf, Proto-oncogene B-Raf, p94, v-Raf murine sarcoma viral oncogene homolog B1, BRAF, BRAF1, RAFB1
UniProt
P15056
Reactivity
Human
Immunogen
This BRAF Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S445 of human BRAF.
Target
BRAF (HGNC:1097)
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Signal Transduction
Dilution
DB - 1:500
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Molecular Weight
84437 Da
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Notes
For research use only.
Prediction Reactivity
Mouse
Tested Applications
DOT
NCBI Accession Number
NP_004324.2
Host or Source
Rabbit
Isotype
Rabbit IgG

UniProtKB · P15056

Serine/threonine-protein kinase B-raf

BRAF_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P15056
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
BRAF
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
2.7.11.1
Processing
—
Secondary accessions
A4D1T4, B6HY61, B6HY62, B6HY63, B6HY64, B6HY65, B6HY66, Q13878, Q3MIN6, Q9UDP8, Q9Y6T3
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationIsopeptide bondMethylationPhosphoproteinUbl conjugation

Molecular function

Allosteric enzymeKinaseSerine/threonine-protein kinaseTransferase

Ligand

ATP-bindingMetal-bindingNucleotide-bindingZinc

Disease

CardiomyopathyDeafnessDisease variantEctodermal dysplasiaIntellectual disabilityProto-oncogene

Cellular component

Cell membraneCytoplasmMembraneNucleus

Coding sequence diversity

Chromosomal rearrangement

Domain

Zinc-finger

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