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Phospho-B-Raf-S445 polyclonal antibody

CAT: 0013-GTR18040566-01Size: 50 μLDry Ice: NoHazardous: No
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CAT#:0013-GTR18040566-01Size:50 μL
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Description
Rabbit polyclonal antibody to Raf-B (phospho-S445)
Product Name Alternative
BRAF; B-RAF1; B-raf; BRAF1; NS7; RAFB1
UniProt
P15056
Reactivity
Human, Rat
Immunogen
A synthetic phosphorylated peptide around S445 of human BRAF (NP_004324.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Signal Transduction
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration
1mg/ml
Dilution
WB1:500 - 1:2000
Form
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH 7.2
Molecular Weight
100kDa
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
WB
Host or Source
Rabbit
Preservative
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH 7.2

UniProtKB · P15056

Serine/threonine-protein kinase B-raf

BRAF_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P15056
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
BRAF
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
2.7.11.1
Processing
—
Secondary accessions
A4D1T4, B6HY61, B6HY62, B6HY63, B6HY64, B6HY65, B6HY66, Q13878, Q3MIN6, Q9UDP8, Q9Y6T3
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationIsopeptide bondMethylationPhosphoproteinUbl conjugation

Molecular function

Allosteric enzymeKinaseSerine/threonine-protein kinaseTransferase

Ligand

ATP-bindingMetal-bindingNucleotide-bindingZinc

Disease

CardiomyopathyDeafnessDisease variantEctodermal dysplasiaIntellectual disabilityProto-oncogene

Cellular component

Cell membraneCytoplasmMembraneNucleus

Coding sequence diversity

Chromosomal rearrangement

Domain

Zinc-finger

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