Anti-Creatine Phosphokinase-BB (CK-BB)(CPTC-CKB-2), CF647 conjugate

• Description:

  Creatine kinases (CK) are a large family of isoenzymes that regulate levels of ATP in subcellular compartments, where they provide ATP at sites of fluctuating energy demand by the transfer of phosphates between creatine and adenine nucleotides. CKs provide the energy of phosphate hydrolysis necessary to drive the normal function of many cellular systems. In cells, the cytosolic CK enzymes consist of two subunits, which can be either B (brain type) or M (muscle type). There are three different isoenzymes: CKMM, CKBB and CKMB. This MAb recognizes the CKBB isoenzyme and does not react with the B subunit in CKMB. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

• Synonyms:

  BCK; Brain creatine kinase; Ckb; Creatine kinase B chain; Creatine kinase B-type; Creatine Kinase BB Isoenzyme; Creatine phosphokinase BB; Epididymis luminal protein 211; Epididymis secretory protein Li 29; HEL 211

• UNSPSC:

  41116161

• UNSPSC Description:

  Primary and secondary antibodies for multiple methodology immunostaining detection application

• Gene Name:

  CKB

• Gene ID:

  1152

• NCBI Gene ID:

  173724

• UniProt:

  P12277

• Cellular Locus:

  Cytoplasmic

• Host:

  Mouse

• Species Reactivity:

  Human

• Immunogen:

  Recombinant human full-length CKB protein

• Target Antigen:

  Creatine Phosphokinase-BB

• Clonality:

  Monoclonal

• Isotype:

  IgG2b κ

• Clone:

  CPTC-CKB-2

• Conjugation:

  CF647

• Source:

  Animal

• Applications:

  WB (verified)

• Validated Applications:

  WB

• Positive Control:

  SH-SY5Y, HEK-293 and Cerebellum.

• Concentration:

  0.1 mg/mL

• Buffer:

  PBS, 0.1% BSA, 0.05% azide

• Molecular Weight:

  42 kDa

• Shipping Conditions:

  Room temperature

• Storage Conditions:

  4°C; Protect from light; Stable at room temperature or 37°C (98°F) for 7 days.

• Shelf Life:

  2 years

• CAS Number:

  9007-83-4