CD8b, Mouse (H35-17.2), 1mg/mL

CAT: 0037-BNUM2003-50Size: 1x 50 µLDry Ice: NoHazardous: No

1 / 1

CAT#:0037-BNUM2003-50Size:1x 50 µL

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Quick Request Actions

Description

This rat monoclonal antibody reacts with the mouse CD8 beta molecule. The CD8 beta chain associates with the CD8 alpha chain to form the CD8 alpha/beta heterodimer expressed on the surface of a majority of thymocytes, and on peripheral cytotoxic alpha beta TCR T cells. This monoclonal antibody identifies cytotoxic/suppressor T-cells that interact with MHC class I bearing targets. CD8 is thought to play a role in the process of T-cell mediated killing. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

CAS Number

9007-83-4

Synonyms

CD8b antigen; CD8 antigen beta polypeptide 1 (p37) ; CD8 beta; CD8B1; Leu2; Ly3; LYT3; P37; T lymphocyte surface glycoprotein beta chain; T-cell surface glycoprotein CD8 beta chain

UNSPSC

41116161

UNSPSC Description

Primary and secondary antibodies for multiple methodology immunostaining detection application

Gene Name

Cd8b1 (Mouse)

Gene ID

12526

NCBI Gene ID

3331

UniProt

P10300

Swiss Prot

P10300

Host

Rat

Species Reactivity

Mouse

Reactivity

CD8b

Immunogen

Five day mixed leukocyte culture population, C57BL/6 anti-BALB/c

Target Antigen

CD8b,

Clonality

Monoclonal

Clone

H35-17.2

Type

Primary

Source

Animal

Origin

Animal

Applications

Flow, surface (published) |Functional studies (published)

Positive Control

MPBMC's or Thymus.

Stability

2 years

Concentration

1 mg/mL

Buffer

PBS, no BSA, no azide

Molecular Weight

37 kDa

References & Citations

Note: References for this clone sold by other suppliers may be listed for expected applications. Infection Immunity (1994) 62(5): 1820-1829. (functional studies) Meth Mol Biol vol 1559. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-6786-5_2 (Flow, surface)

Shipping Conditions

RT (ND)

Storage Conditions

Stable at room temperature or 37°C (98°F) for 7 days.

Shelf Life

Guaranteed for at least 24 months from date of receipt when stored as recommended

Fragment

IgG2b, kappa

Species

Rattus norvegicus (laboratory rat)

Classification

PBS, no BSA, no sodium azide (CAS 26628-22-8)

Conjugate

Purified, BSA-free

UniProtKB · P10300

T-cell surface glycoprotein CD8 beta chain

CD8B_MOUSE · Mus musculus

View on UniProt ↗

Primary accession: P10300
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: Cd8b
Protein existence: 1: Evidence at protein level
Organism: Mus musculus (Mouse)
Taxonomy ID: 10090
Alternative names: —
EC number: —
Processing: Precursor
Secondary accessions: Q31127, Q60966, Q61811

Protein keywords

Technical term

3D-structureReference proteome

Biological process

Adaptive immunityImmunity

PTM

Disulfide bondGlycoprotein

Domain

Immunoglobulin domainSignalTransmembraneTransmembrane helix

Cellular component

Membrane

Product Datasheet

Related Products

Catalog	Name
BNC682003-500	CD8b, Mouse (H35-17.2), CF568 conjugate, 0.1mg/mL
BNC742003-500	CD8b, Mouse (H35-17.2), CF740 conjugate, 0.1mg/mL
BNC472003-500	CD8b, Mouse (H35-17.2), CF647 conjugate, 0.1mg/mL
BNC742003-100	CD8b, Mouse (H35-17.2), CF740 conjugate, 0.1mg/mL
BNC042003-100	CD8b, Mouse (H35-17.2), CF405S conjugate, 0.1mg/mL
BNC682003-100	CD8b, Mouse (H35-17.2), CF568 conjugate, 0.1mg/mL
BNC042003-500	CD8b, Mouse (H35-17.2), CF405S conjugate, 0.1mg/mL
BNCB2003-100	CD8b, Mouse (H35-17.2), Biotin conjugate, 0.1mg/mL
BNC942003-500	CD8b, Mouse (H35-17.2), CF594 conjugate, 0.1mg/mL
BNCB2003-500	CD8b, Mouse (H35-17.2), Biotin conjugate, 0.1mg/mL

Alternative Products

Catalog	Name
30-2543-0.1	Anti-Mouse CD8b PE (Clone : H35-17.2)
30-2541-0.1	Anti-Mouse CD8b Antibody (Clone : H35-17.2)
36-3819-100	Anti-CD8b, Mouse Monoclonal Antibody (Clone: H35-17.2)
FMC84720	Anti-Mouse CD8b/Lyt3 Antibody (35.17.2#)
FMC84724	Anti-Mouse CD8b/Lyt3 Antibody (35.17.2#), PerCP
FMC84721	Anti-Mouse CD8b/Lyt3 Antibody (35.17.2#), FITC
MY433227-01	Anti-Mouse CD8b/Lyt3 Antibody (35.17.2#), PE
MY433237-01	Anti-Mouse CD8b/Lyt3 Antibody (35.17.2#), APC
WM2263-01	U-Blot® Mouse CD8b/Lyt3 Antibody (35.17.2#)
PTX23529	Anti-Mouse CD8b/Lyt3 Monoclonal Antibody (35.17.2#), PE