CD8b, Mouse (H35-17.2), CF405S conjugate, 0.1mg/mL

CAT: 0037-BNC042003-500Size: 1x 500 µLDry Ice: NoHazardous: No
CAT#:0037-BNC042003-500Size:1x 500 µL
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Description
This rat monoclonal antibody reacts with the mouse CD8 beta molecule. The CD8 beta chain associates with the CD8 alpha chain to form the CD8 alpha/beta heterodimer expressed on the surface of a majority of thymocytes, and on peripheral cytotoxic alpha beta TCR T cells. This monoclonal antibody identifies cytotoxic/suppressor T-cells that interact with MHC class I bearing targets. CD8 is thought to play a role in the process of T-cell mediated killing. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
CAS Number
9007-83-4
Synonyms
CD8b antigen; CD8 antigen beta polypeptide 1 (p37) ; CD8 beta; CD8B1; Leu2; Ly3; LYT3; P37; T lymphocyte surface glycoprotein beta chain; T-cell surface glycoprotein CD8 beta chain
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
Cd8b1 (Mouse)
Gene ID
12526
NCBI Gene ID
3331
UniProt
P10300
Swiss Prot
P10300
Host
Rat
Species Reactivity
Mouse
Reactivity
CD8b
Immunogen
Five day mixed leukocyte culture population, C57BL/6 anti-BALB/c
Target Antigen
CD8b,
Clonality
Monoclonal
Clone
H35-17.2
Type
Primary
Source
Animal
Origin
Animal
Applications
Flow, surface (published) |Functional studies (published)
Positive Control
MPBMC's or Thymus.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
37 kDa
References & Citations
Note: References for this clone sold by other suppliers may be listed for expected applications. Infection Immunity (1994) 62(5): 1820-1829. (functional studies) Meth Mol Biol vol 1559. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-6786-5_2 (Flow, surface)
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG2b, kappa
Species
Rattus norvegicus (laboratory rat), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF405S
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