Anti-IL-10R1, Mouse (Interleukin-10 Receptor 1) (CD210)(1B1.3a), Biotin conjugate
CAT:
37-BNCB2001-100
Size:
100 µL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Anti-IL-10R1, Mouse (Interleukin-10 Receptor 1) (CD210)(1B1.3a), Biotin conjugate
- Description: This monoclonal antibody recognizes Mouse Interleukin-10 receptor 1 (IL-10R1), a cell surface glycoprotein of approximately 110 kDa. Its epitope is localized in the ligand-binding domain in the extracellular region of Mouse IL-10R1. This antibody blocks the binding of IL-10 to its receptor. IL-10R1 is a class II cytokine receptor expressed on thymocytes, T cells, B cells, NK cells, monocytes and macrophages. Binding of IL-10 to its receptor initiates JAK/STAT signaling that leads to B cell proliferation and inhibition of macrophage activation. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- Synonyms: CD210 antigen; CDw210a; IBD28; IL10R alpha; IL-10R subunit 1; IL-10R1; IL10RA IL10RIL-10R subunit alpha; interleukin 10 receptor; alpha; interleukin-10 receptor alpha chain; Interleukin-10 receptor subunit 1
- CAS Number: 9007-83-4
- UNSPSC: 41116161
- UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
- Gene ID: 16154
- NCBI Gene ID: 379327
- UniProt: Q61727
- Cellular Locus: Plasma membrane
- Host: Rat
- Species Reactivity: Mouse
- Immunogen: Purified recombinant extracellular region of Mouse IL10RA
- Target Antigen: IL-10R1,
- Clonality: Monoclonal
- Isotype: IgG1 κ
- Clone: 1B1.3a
- Conjugation: Biotin
- Source: Animal
- Applications: Flow, surface (published) | Functional studies (published)
- Validated Applications: FC, Functional assays
- Positive Control: MPBMC's. Spleen, Thymus, Lymph Node, Placenta, Lung or Liver.
- Concentration: 0.1 mg/mL
- Buffer: PBS, 0.1% BSA, 0.05% azide
- Molecular Weight: 90-110 kDa
- References & Citations: Note: References for this clone sold by other suppliers may be listed for expected applications. J Immunol (2008) 181:5545-5550. (neutralization) PLoS One (2017) 12(10): e0186317. (Flow, surface)
- Shipping Conditions: Room temperature
- Storage Conditions: 4°C; Stable at room temperature or 37°C (98°F) for 7 days.
- Shelf Life: 2 years