Anti-Cytokeratin, Multi (Epithelial Marker)(rKRT/457), Biotin conjugate
CAT:
37-BNCB1876-500
Size:
500 µL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Anti-Cytokeratin, Multi (Epithelial Marker)(rKRT/457), Biotin conjugate
- Description: Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6. 0) subfamilies. This antibody recognizes acidic (Type I or LMW) and basic (Type II or HMW) cytokeratins, including 59 kDa (CK4); 58 kDa (CK5); 56 kDa (CK6); 52 kDa (CK8); 56. 5 kDa (CK10); 53 kDa (CK13) and 45 kDa (CK18). This is a broad-spectrum antibody, which has been reported to differentiate epithelial tumors from non-epithelial tumors. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- Synonyms: K1B; KRT1B; Keratin, type II cytoskeletal 1b; K77; CK-1B; Keratin 1B; Keratin-77; Cytokeratin-1B; Type-II Keratin Kb39
- CAS Number: 9007-83-4
- UNSPSC: 41116161
- UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
- Gene ID: 3851; 3852; 3853; 3854; 286887; 3856; 3858; 3860; 3875
- UniProt: P02538; P04259; P13647; P19013; P48668
- Cellular Locus: Cytoskeleton
- Host: Mouse
- Species Reactivity: Cow, Frog, Goat, Guinea pig, Human, Monkey, Mouse, Pig, Rat
- Immunogen: Keratin-enriched preparation from cultured human epithelial cells
- Target Antigen: Cytokeratin, Multi
- Clonality: Recombinant Monoclonal
- Isotype: IgG1 κ
- Clone: rKRT/457
- Conjugation: Biotin
- Source: Animal
- Applications: IHC, FFPE (verified)
- Validated Applications: IHC, FFPE
- Field of Research: Cancer, Cytoskeleton
- Positive Control: A431 cells, Skin, Colon carcinoma
- Concentration: 0.1 mg/mL
- Buffer: PBS, 0.1% BSA, 0.05% azide
- Molecular Weight: Multiple
- Shipping Conditions: Room temperature
- Storage Conditions: 4°C; Stable at room temperature or 37°C (98°F) for 7 days.
- Shelf Life: 2 years