Anti-Cytokeratin, Multi (Epithelial Marker)(KRT/1877R)

• Description:

  Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6. 0) subfamilies. This antibody recognizes acidic (Type I or LMW) and basic (Type II or HMW) cytokeratins, including 59 kDa (CK4); 58 kDa (CK5); 56 kDa (CK6); 52 kDa (CK8); 56. 5 kDa (CK10); 53 kDa (CK13) and 45 kDa (CK18). This is a broad-spectrum antibody, which has been reported to differentiate epithelial tumors from non-epithelial tumors. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

• Synonyms:

  K1B; KRT1B; Keratin, type II cytoskeletal 1b; K77; CK-1B; Keratin 1B; Keratin-77; Cytokeratin-1B; Type-II Keratin Kb39

• UNSPSC:

  41116161

• UNSPSC Description:

  Primary and secondary antibodies for multiple methodology immunostaining detection application

• Gene ID:

  3851; 3852; 3853; 3854; 286887; 3856; 3858; 3860; 3875

• UniProt:

  P02538; P04259; P13647; P19013; P48668

• Cellular Locus:

  Cytoskeleton

• Host:

  Rabbit

• Species Reactivity:

  Cow, Frog, Goat, Guinea pig, Human, Monkey, Mouse, Pig, Rat

• Immunogen:

  Keratin-enriched preparation from cultured human epithelial cells

• Target Antigen:

  Cytokeratin, Multi

• Clonality:

  Recombinant Monoclonal

• Isotype:

  IgG

• Clone:

  KRT/1877R

• Conjugation:

  Purified, with BSA

• Source:

  Animal

• Applications:

  IF (verified) | IHC, FFPE (verified)

• Validated Applications:

  IF, IHC, FFPE

• Field of Research:

  Cancer, Cytoskeleton

• Positive Control:

  A431 cells, Skin, Colon carcinoma

• Concentration:

  0.2 mg/mL

• Buffer:

  PBS, 0.05% BSA, 0.05% azide

• Molecular Weight:

  Multiple

• Shipping Conditions:

  Room temperature

• Storage Conditions:

  4°C; Stable at room temperature or 37°C (98°F) for 7 days.

• Shelf Life:

  2 years

• CAS Number:

  9007-83-4