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Lanperisone (hydrochloride)

CAT: 0804-HY-119325A-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-119325A-01Size:1 mg
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Description
Lanperisone hydrochloride is a novel oral muscle relaxant with anticancer activity. Lanperisone hydrochloride produces non-apoptotic cell death by inhibiting monosynaptic and polysynaptic reflex potentials. Lanperisone hydrochloride is also believed to play an important role in the dysregulation of iron metabolism and antioxidant systems to modulate processes associated with ischemic stroke[1].
CAS Number
116287-13-9
Product Name Alternative
NK433
UNSPSC
12352005
Target
Apoptosis
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/lanperisone-hydrochloride.html
Purity
99.65
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
C[C@H](CN1CCCC1)C(C2=CC=C(C=C2)C(F)(F)F)=O.Cl
Molecular Formula
C15H19ClF3NO
Molecular Weight
321.77
References & Citations
[1]Progress of Ferroptosis in Ischemic Stroke and Therapeutic Targets
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Chemical Information

Lanperisone Hydrochloride

Lanperisone hydrochloride is the hydrochloride salt of lanperisone. It is a muscle relaxant. It has a role as a ferroptosis inducer, an antineoplastic agent, a calcium channel blocker, a voltage-gated sodium channel blocker and a muscle relaxant. It contains a lanperisone(1+).

CAS Number116287-13-9
PubChem CID198706
IUPAC Name(2R)-2-methyl-3-pyrrolidin-1-yl-1-[4-(trifluoromethyl)phenyl]propan-1-one;hydrochloride
Molecular FormulaC15H19ClF3NO
Molecular Weight321.76
Topological Polar Surface Area20.3
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count5
Rotatable Bond Count4
Heavy Atom Count21
Formal Charge0
Complexity329
SMILES
C[C@H](CN1CCCC1)C(=O)C2=CC=C(C=C2)C(F)(F)F.Cl
InChI
InChI=1S/C15H18F3NO.ClH/c1-11(10-19-8-2-3-9-19)14(20)12-4-6-13(7-5-12)15(16,17)18;/h4-7,11H,2-3,8-10H2,1H3;1H/t11-;/m1./s1
InChIKey
PHBZFPOOJUGYCR-RFVHGSKJSA-N
Chemical Structure
2D Structure
2D structure of Lanperisone Hydrochloride
CAS: 116287-13-9
CID: 198706
Formula: C15H19ClF3NO
MW: 321.76
Interactive 3D Structure
Loading 3D structure...
Computed Properties
PropertyValue
Molecular Weight321.76
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count5
Rotatable Bond Count4
Exact Mass321.1107264
Monoisotopic Mass321.1107264
Topological Polar Surface Area20.3 Ų
Heavy Atom Count21
Formal Charge0
Complexity329
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count2
Compound Is CanonicalizedYes

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