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BACE1B Antibody (Center)

CAT: 0013-GTR18327835-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0013-GTR18327835-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Purified Rabbit Polyclonal Antibody (Pab)
Product Name Alternative
Beta-secretase 1, Aspartyl protease 2, ASP2, Asp 2, Beta-site amyloid precursor protein cleaving enzyme 1, Beta-site APP cleaving enzyme 1, Memapsin-2, Membrane-associated aspartic protease 2, BACE1, BACE, KIAA1149
UniProt
P56817
Reactivity
Human, Mouse
Immunogen
This BACE1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 169-198 amino acids from the Central region of human BACE1B. Antigen Region: 169-198 aa.
Target
BACE1 (HGNC:933)
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Cell Biology, Neuroscience
Dilution
WB - 1:1000, IHC-P - 1:50-100
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Molecular Weight
55764 Da
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Notes
For research use only.
Tested Applications
IHC-P, WB
NCBI Accession Number
NP_620429.1, NP_620427.1, NP_036236.1, NP_001193978.1, NP_620428.1
Host or Source
Rabbit
Isotype
Rabbit IgG

UniProtKB · P56817

Beta-secretase 1

BACE1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P56817
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
BACE1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
3.4.23.46
Processing
Precursor
Secondary accessions
A0M8W7, B0YIU9, E9PE65, H7BXJ9, Q9BYB9, Q9BYC0, Q9BYC1, Q9UJT5, Q9ULS1
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationDisulfide bondGlycoproteinIsopeptide bondLipoproteinPalmitatePhosphoproteinUbl conjugationZymogen

Coding sequence diversity

Alternative splicing

Molecular function

Aspartyl proteaseHydrolaseProtease

Cellular component

Cell membraneCell projectionCytoplasmic vesicleEndoplasmic reticulumEndosomeGolgi apparatusLysosomeMembrane

Domain

SignalTransmembraneTransmembrane helix

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