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COT (MAP3K8/MEKK8) Antibody (C-term)

CAT: 0013-GTR18326266-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0013-GTR18326266-01Size:50 µL
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Description
Purified Rabbit Polyclonal Antibody (Pab)
Product Name Alternative
Mitogen-activated protein kinase kinase kinase 8, Cancer Osaka thyroid oncogene, Proto-oncogene c-Cot, Serine/threonine-protein kinase cot, Tumor progression locus 2, TPL-2, MAP3K8, COT, ESTF
UniProt
P41279
Reactivity
Human
Immunogen
This COT (MAP3K8/MEKK8) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 414-445 amino acids from the C-terminal region of human COT (MAP3K8/MEKK8) . Antigen Region: 414-445 aa.
Target
MAP3K8
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Signal Transduction
Dilution
WB - 1:1000, IHC-P - 1:50-100
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Molecular Weight
52925 Da
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Notes
For research use only.
Tested Applications
IHC-P, WB
NCBI Accession Number
NP_001231063.1, NP_005195.2
Host or Source
Rabbit
Isotype
Rabbit IgG

UniProtKB · P41279

Mitogen-activated protein kinase kinase kinase 8

M3K8_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P41279
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
MAP3K8
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
2.7.11.25
Processing
—
Secondary accessions
A8K2Q5, D3DRX1, Q14275, Q5T855, Q9HC81
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative initiation

Ligand

ATP-bindingMagnesiumMetal-bindingNucleotide-binding

Biological process

Cell cycleImmunity

Cellular component

Cytoplasm

Molecular function

KinaseSerine/threonine-protein kinaseTransferase

PTM

Phosphoprotein

Disease

Proto-oncogene

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