GC Antibody (Center)

CAT: 0013-GTR18325600-01Size: 50 µLDry Ice: NoHazardous: No

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CAT#:0013-GTR18325600-01Size:50 µL

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

Affinity Purified Rabbit Polyclonal Antibody (Pab)

Product Name Alternative

Glucosylceramidase, Acid beta-glucosidase, Alglucerase, Beta-glucocerebrosidase, Beta-GC, D-glucosyl-N-acylsphingosine glucohydrolase, Imiglucerase, GBA, GC, GLUC

UniProt

P04062

Reactivity

Human, Mouse

Immunogen

This GC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 337-365 amino acids of human GC. Antigen Region: 337-365 aa.

Target

GBA1 (HGNC:4177)

Clonality

Polyclonal

Conjugation

Unconjugated

Field of Research

Cancer Biology, Cell Biology, Metabolism Research, Neuroscience, Signal Transduction

Dilution

WB - 1:2000, IHC-P-Leica - 1:500, FC - 1:25

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Molecular Weight

59716 Da

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles

Notes

For research use only.

Prediction Reactivity

Porcine

Tested Applications

FC, IHC-P, WB

NCBI Accession Number

NP_001005741.1, NP_001005742.1, NP_000148.2

Host or Source

Rabbit

Isotype

Rabbit IgG

UniProtKB · P04062

Lysosomal acid glucosylceramidase

GBA1_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: P04062
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: GBA1
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: Lysosomal acid GCase
EC number: 3.2.1.45
Processing: Precursor
Secondary accessions: A8K796, B7Z5G2, B7Z6S1, J3KQG4, J3KQK9, Q16545, Q4VX22, Q6I9R6, Q9UMJ8

Protein keywords

Technical term

3D-structureDirect protein sequencingPharmaceuticalProteomics identificationReference proteome

Coding sequence diversity

Alternative initiationAlternative splicing

Biological process

Cholesterol metabolismLipid metabolismSphingolipid metabolismSteroid metabolismSterol metabolism

Disease

Disease variantGaucher diseaseIchthyosisNeurodegenerationParkinson diseaseParkinsonism

PTM

Disulfide bondGlycoprotein

Molecular function

GlycosidaseGlycosyltransferaseHydrolaseTransferase

Cellular component

LysosomeMembrane

Domain

Signal

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