Carmustine

• Description:

  Carmustine is an antitumor chemotherapeutic agent, which works by akylating DNA and RNA.

• Product Name Alternative:

  BCNU

• UNSPSC:

  12352211

• Hazard Statement:

  H300, H350, H360

• Target:

  DNA Alkylator/Crosslinker

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/Carmustine.html

• Concentration:

  10mM

• Purity:

  99.96

• Solubility:

  DMSO : 100 mg/mL (ultrasonic) |H2O : 100 mg/mL (ultrasonic)

• Smiles:

  O=C (NCCCl) N (CCCl) N=O

• Molecular Formula:

  C5H9Cl2N3O2

• Molecular Weight:

  214.05

• Precautions:

  H300, H350, H360

• References & Citations:

  [1]Hung CF. Effects of carmustine and lomustine on arylamine N-acetyltransferase activity and 2-aminofluorene-DNA adducts in rat glial tumor cells. Neurochem Res. 2000 Jun;25 (6) :845-51.|[2]Demir A, et al. The effect of trimetazidine on intrahepatic cholestasis caused by carmustine in rats. Hepatol Res. 2001 May 1;20 (1) :133-143.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C (Powder, protect from light)

• Scientific Category:

  Reference compound1

• Clinical Information:

  Launched

• CAS Number:

  154-93-8