Sheep anti bcl-2

Sheep anti bcl-2

• Background: Human hematopoetic malignancies are often characterized by gene rearrangements that deregulate gene expression. Antibodies to Human bcl-2 (B cell leukemia/lymphoma 2) are directed against the gene isolated at the chromosomal breakpoint t(14;18) Bcl-2 which suppress programmed cell death (apoptosis) and appears to be modulated by association with bax, a cell death promoter.
• Synonyms: hbcl2, Sheep Anti Human bcl 2, bcl-2
• CAS Number: 9007-83-4
• UniProt: P10415
• Host: Sheep
• Species Reactivity: Human, Dog, Rat
• Isotype: IgG
• Conjugation: Unconjugated
• Type: Polyclonal Antibody
• Source: Sheep were immunized with full length recombinant bcl-2 protein
• Applications: WB, IP, IF
• Field of Research: Apoptosis
• Purification Method: Ammonium Sulfate Precipitation
• Assay Principle: Western Blots at 1:5000, Immunoprecipitation – Empirical, Immunofluorescence 1:5000.
• Stability: See expiration date on vial
• Concentration: See vial for Concentration
• Form: Provided as solution in phosphate buffered saline with 0,08% sodium azide
• Precautions: This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving Humans or animals.
• References & Citations: 1. Chida, Y., et al. 'The hepatic sympathetic nerve plays a critical role in preventing Fas induced liver injury in mice.' Gut 2005, 54, 994-1002 (Product specific)
• Shipping Conditions: Ambient Temperature
• Storage Conditions: Product should be stored at -20ºC; Aliquot to avoid freeze/thaw cycles
• Functional Analysis: WB