SIM-6080

• UNSPSC Description:

  SIM-6080 is a calcium antagonist and inhibits the proliferation of rat aortic myocytes and reduces aortic atherosclerosis in rabbits[1][2].

• Target Antigen:

  Calcium Channel

• Type:

  Reference compound

• Related Pathways:

  Membrane Transporter/Ion Channel;Neuronal Signaling

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/sim-6080.html

• Smiles:

  FC1=CC=C(C(CCN(CCN(CC2=CC(OC)=C(C(OC)=C2)OC)C)C)C3=CC=C(C=C3)F)C=C1

• Molecular Weight:

  498.60

• References & Citations:

  [1]Bernini F, et al. In vitro inhibition of arterial myocyte growth and stimulation of low density lipoprotein metabolism by SIM 6080, a new calcium antagonist. Pharmacol Res. 1990;22(1):27-35. |[2]Maggi FM, et al. SIM 6080, a new calcium antagonist, reduces aortic atherosclerosis in cholesterol-fed rabbits. Pharmacol Res. 1993;28(3):219-227.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  118790-68-4