SIM-6080

• Description :

  SIM-6080 is a calcium antagonist and inhibits the proliferation of rat aortic myocytes and reduces aortic atherosclerosis in rabbits[1][2].

• UNSPSC :

  12352005

• Target :

  Calcium Channel

• Type :

  Reference compound

• Related Pathways :

  Membrane Transporter/Ion Channel; Neuronal Signaling

• Field of Research :

  Metabolic Disease

• Assay Protocol :

  https://www.medchemexpress.com/sim-6080.html

• Smiles :

  FC1=CC=C(C(CCN(CCN(CC2=CC(OC)=C(C(OC)=C2)OC)C)C)C3=CC=C(C=C3)F)C=C1

• Molecular Formula :

  C29H36F2N2O3

• Molecular Weight :

  498.60

• References & Citations :

  [1]Bernini F, et al. In vitro inhibition of arterial myocyte growth and stimulation of low density lipoprotein metabolism by SIM 6080, a new calcium antagonist. Pharmacol Res. 1990;22 (1) :27-35. |[2]Maggi FM, et al. SIM 6080, a new calcium antagonist, reduces aortic atherosclerosis in cholesterol-fed rabbits. Pharmacol Res. 1993;28 (3) :219-227.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [118790-68-4]