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DC-BPi-11 (hydrochloride)

CAT:
804-HY-141703A-06
Size:
100 mg
Price:
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  • Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
  • Dry Ice Shipment: No
DC-BPi-11 (hydrochloride) - image 1

DC-BPi-11 (hydrochloride)

  • UNSPSC Description: DC-BPi-11 hydrochloride is an inhibitor of bromodomain PHD finger transcription factor (BPTF), with an IC50 value of 698 nM. DC-BPi-11 hydrochloride shows remarkable inhibition against leukemia cell proliferation[1].
  • Target Antigen: Epigenetic Reader Domain
  • Type: Reference compound
  • Related Pathways: Epigenetics
  • Applications: Cancer-programmed cell death
  • Field of Research: Cancer
  • Assay Protocol: https://www.medchemexpress.com/dc-bpi-11-hydrochloride.html
  • Solubility: DMSO : 10 mg/mL (ultrasonic;warming;heat to 60°C)
  • Smiles: CN(C)CCCN1C=CC2=C1C=CC(C3=NC(S(C)(=O)=O)=NC4=C3C=CN4)=C2.[H]Cl
  • Molecular Weight: 433.95
  • References & Citations: [1]Lu T, et al. Discovery of High-Affinity Inhibitors of the BPTF Bromodomain. J Med Chem. 2021 Aug 26;64(16):12075-12088.
  • Shipping Conditions: Blue Ice
  • Clinical Information: No Development Reported