SingleFlowEx CD2 APC

• Description:

  SingleFlowEx is fluorochrome-labeled monoclonal antibody single reagent for use in laboratory-developed multicolor flow cytometry tests in order to examine human clinical samples. SingleFlowEx can be used in various multicolor combinations. Laboratory shall establish the SingleFlowEx performance characteristics in conjunction with other reagents in normal and pathological samples.

• Certification:

  RUO (GMP)

• Clone:

  LT2

• Applications:

  FC (QC tested)

• Concentration:

  0.020 mg/mL

• Format:

  APC

• Buffer:

  Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

• Components:

  1 vial of monoclonal antibody reagent.The content (1 mL) is sufficient for min. 100 Tests.

• References & Citations:

  *Filatov AV, Bachurin PS, Markova NA, Surnakova NE: [A panel of monoclonal antibodies against human lymphocyte antigens] Eksp Onkol. 1989;11 (2) :28-32., URL: https://pubmed.ncbi.nlm.nih.gov/2737128/, *Leukocyte Typing VI., Kishimoto T. et al. (Eds.), Garland Publishing Inc. (1997) ., URL: , *Gannon GA, Rhind SG, Suzui M, Zamecnik J, Sabiston BH, Shek PN, Shephard RJ: beta-Endorphin and natural killer cell cytolytic activity during prolonged exercise. Is there a connection? Am J Physiol. 1998 Dec;275 (6 Pt 2) :R1725-34., URL: https://www.ncbi.nlm.nih.gov/pubmed/9843861?itool=, *Lin CW, Liu TY, Chen SU, Wang KT, Medeiros LJ, Hsu SM: CD94 1A transcripts characterize lymphoblastic lymphoma/leukemia of immature natural killer cell origin with distinct clinical features. Blood. 2005 Nov 15;106 (10) :3567-74. , URL: https://www.ncbi.nlm.nih.gov/pubmed/16046525?itool, *Use of this product has not been published., URL:

• Other References:

  *Pawlowski NN, Struck D, Grollich K, Kuhl AA, Zeitz M, Liesenfeld O, Hoffmann JC: CD2 deficiency partially prevents small bowel inflammation and improves parasite control in murine Toxoplasma gondii infection. World J Gastroenterol. 2007 Aug 21;13 (31) :4207-13., URL: https://pubmed.ncbi.nlm.nih.gov/17696249/, *Zhu DM, Dustin ML, Cairo CW, Thatte HS, Golan DE: Mechanisms of cellular avidity regulation in CD2-CD58-mediated T cell adhesion. ACS Chem Biol. 2006 Nov 21;1 (10) :649-58., URL: https://pubmed.ncbi.nlm.nih.gov/17168569/, *Dustin ML: Adhesive bond dynamics in contacts between T lymphocytes and glass-supported planar bilayers reconstituted with the immunoglobulin-related adhesion molecule CD58. J Biol Chem. 1997 Jun 20;272 (25) :15782-8., URL: https://pubmed.ncbi.nlm.nih.gov/9188475/, *Pawlowski NN, Struck D, Grollich K, Kuhl AA, Zeitz M, Liesenfeld O, Hoffmann JC: CD2 deficiency partially prevents small bowel inflammation and improves parasite control in murine Toxoplasma gondii infection. World J Gastroenterol. 2007 Aug 21;13 (31) :4207-13., URL: https://pubmed.ncbi.nlm.nih.gov/17696249/

• Storage Conditions:

  Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.