Iobenguane (sulfate) (Standard)

• UNSPSC Description:

  Iobenguane (sulfate) (Standard) is the analytical standard of Iobenguane (sulfate). This product is intended for research and analytical applications. Iobenguane sulfate (MIBG sulfate) is an analogue of the neurotransmitter norepinephrine with antitumor activity. Radioiodinated Iobenguane sulfate is clinically used as a tumor-targeted radiopharmaceutical in the diagnosis and treatment of adrenergic tumors. Iobenguane sulfate is a high-affinity substrate for cholera toxin that interferes with cellular mono(ADP-ribosylation)[1][2].

• Target Antigen:

  Others

• Type:

  Reference Standards

• Related Pathways:

  Others

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/iobenguane-sulfate-standard.html

• Smiles:

  NC(NCC1=CC=CC(I)=C1)=N.O=S(O)(O)=O.[1/2]

• Molecular Weight:

  324.13

• References & Citations:

  [1]Loesberg C, et al. Meta-iodobenzylguanidine (MIBG), a novel high-affinity substrate for cholera toxin that interferes with cellular mono(ADP-ribosylation). Biochim Biophys Acta. 1990 Jan 19;1037(1):92-9.

• Shipping Conditions:

  Room temperature

• CAS Number:

  87862-25-7