Iobenguane (sulfate)

• Product Name Alternative:

  MIBG (sulfate)

• UNSPSC Description:

  Iobenguane sulfate (MIBG sulfate) is an analogue of the neurotransmitter norepinephrine with antitumor activity. Radioiodinated Iobenguane sulfate is clinically used as a tumor-targeted radiopharmaceutical in the diagnosis and treatment of adrenergic tumors. Iobenguane sulfate is a high-affinity substrate for cholera toxin that interferes with cellular mono(ADP-ribosylation)[1][2].

• Target Antigen:

  Others

• Type:

  Reference compound

• Related Pathways:

  Others

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/iobenguane-sulfate.html

• Purity:

  99.78

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  NC(NCC1=CC=CC(I)=C1)=N.O=S(O)(O)=O.[1/2]

• Molecular Weight:

  324.13

• References & Citations:

  [1]Loesberg C, et al. Meta-iodobenzylguanidine (MIBG), a novel high-affinity substrate for cholera toxin that interferes with cellular mono(ADP-ribosylation). Biochim Biophys Acta. 1990 Jan 19;1037(1):92-9.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, sealed storage, away from moisture)

• Clinical Information:

  Launched

• CAS Number:

  87862-25-7