2',5-Difluoro-2'-deoxy-1-arabinosyluracil

• UNSPSC Description:

  5-Fluoro-1-((2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione (2',5-difluoro-2'-deoxy-1-arabinosyluracil) is a uridine analogue. Uridine has potential antiepileptic effects, and its analogs can be used to study anticonvulsant and anxiolytic activities, as well as to develop new antihypertensive agents[1].

• Target Antigen:

  Nucleoside Antimetabolite/Analog

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/2-5-difluoro-2-deoxy-1-arabinosyluracil.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O[C@H]1[C@H](F)[C@H](N2C(NC(C(F)=C2)=O)=O)O[C@@H]1CO.C

• Molecular Weight:

  280.23

• References & Citations:

  [1]Connolly GP, et al. Uridine and its nucleotides: biological actions, therapeutic potentials. Trends Pharmacol Sci. 1999 May;20(5):218-25.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  69123-95-1