2',5-Difluoro-2'-deoxy-1-arabinosyluracil

2',5-Difluoro-2'-deoxy-1-arabinosyluracil

• CAS Number: 69123-95-1
• UNSPSC Description: 5-Fluoro-1-((2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione (2',5-difluoro-2'-deoxy-1-arabinosyluracil) is a uridine analogue. Uridine has potential antiepileptic effects, and its analogs can be used to study anticonvulsant and anxiolytic activities, as well as to develop new antihypertensive agents[1].
• Target Antigen: Nucleoside Antimetabolite/Analog
• Type: Reference compound
• Related Pathways: Cell Cycle/DNA Damage
• Applications: Cancer-programmed cell death
• Field of Research: Others
• Assay Protocol: https://www.medchemexpress.com/2-5-difluoro-2-deoxy-1-arabinosyluracil.html
• Solubility: 10 mM in DMSO
• Smiles: O[C@H]1[C@H](F)[C@H](N2C(NC(C(F)=C2)=O)=O)O[C@@H]1CO.C
• Molecular Weight: 280.23
• References & Citations: [1]Connolly GP, et al. Uridine and its nucleotides: biological actions, therapeutic potentials. Trends Pharmacol Sci. 1999 May;20(5):218-25.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported