2'-Deoxy-2'-fluoro-5-iodouridine

• UNSPSC Description:

  2'-Deoxy-2'-fluoro-5-iodouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

• Target Antigen:

  Nucleoside Antimetabolite/Analog

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/2-deoxy-2-fluoro-5-iodouridine.html

• Purity:

  98.99

• Solubility:

  DMSO : 125 mg/mL (ultrasonic)

• Smiles:

  O[C@H]1[C@@H](F)[C@H](N2C(NC(C(I)=C2)=O)=O)O[C@@H]1CO

• Molecular Weight:

  372.09

• References & Citations:

  [1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, sealed storage, away from moisture and light)

• Clinical Information:

  No Development Reported

• CAS Number:

  55612-21-0