Products for Research Use Only

Interferon gamma Antibody

CAT: 0013-GTR18317508Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR18317508Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Recognizes a protein of 20-25kDa, identified as human interferon. This mAb is specific to human IFN-gamma and recognizes both recombinant and native human IFN-gamma. T lymphocytes and NK cells mainly produce IFN-gamma. It is a pleiotropic cytokine involved in the regulation of nearly all phases of immune and inflammatory responses, including the activation, growth and differentiation of T cell, B cells, macrophages, NK cells and other cell types such as endothelial cells and fibroblasts. It has weak anti-viral and anti-proliferative activity, and potentiates the antiviral and anti-tumor effects of IFN-A/B (type I interferon) .
UniProt
P01579
Reactivity
Human
Immunogen
Purified recombinant human IFN-gamma was used as the immunogen for the Interferon gamma antibody.
Clonality
Monoclonal
Clone
IFNG/464
Conjugation
Unconjugated
Field of Research
Immunology & Inflammation
Purification
Protein A/G affinity
Dilution
Flow cytometry: 1-2ug/million cells, Immunofluorescence: 1-2ug/ml
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
Optimal dilution of the Interferon gamma antibody should be determined by the researcher.
Tested Applications
FACS, IF
Host or Source
Mouse
Preservative
1 mg/ml in 1X PBS; rAlbumin free, sodium azide free
Isotype
Mouse IgG1, kappa

UniProtKB · P01579

Interferon gamma

IFNG_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P01579
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
IFNG
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
IFN-gamma
EC number
—
Processing
Precursor
Secondary accessions
B5BU88, Q53ZV4
Protein keywords

Technical term

3D-structureDirect protein sequencingPharmaceuticalProteomics identificationReference proteome

Biological process

Antiviral defenseGrowth regulation

PTM

Cleavage on pair of basic residuesGlycoproteinPyrrolidone carboxylic acid

Molecular function

Cytokine

Cellular component

Secreted

Domain

Signal

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