Products for Research Use Only
RegisterLogin

IgD Antibody / Heavy chain

CAT: 0013-GTR18317491Size: 100 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR18317491Size:100 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Immunoglobulins are four-chain, Y-shaped, monomeric structures comprised of two identical heavy chains and two identical light chains held together through interchain disulfide bonds. The chains form two domains, the Fab (antigen binding) fragment and the Fc (constant) fragment. Immunoglobulin D (IgD) exists as a monomer with delta heavy chains and either kappa or lambda light chains. It plays a biological role as a transmembrane receptor molecule, co-expressed with IgM on the surface of mature/naive B cells. In particular, it is found on spleen B cell surfaces. Compared to IgM, IgD exists in much lower numbers and is not expressed on immature B cells. IgD surface expression on B cells is regulated in part by IL-27. In mice, the inhibition of this immunoglobulin isotype does not cause a significant change to the immune system.
UniProt
P01880
Reactivity
Human
Immunogen
Recombinant full-length human IGHD protein was used as the immunogen for the IgD antibody.
Clonality
Recombinant
Clone
IGHD/2730R
Conjugation
Unconjugated
Field of Research
Immunology & Inflammation
Purification
Protein A/G affinity
Dilution
Immunohistochemistry (FFPE) : 1-2ug/ml for 30 minutes at RT
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
Optimal dilution of the IgD antibody should be determined by the researcher.
Tested Applications
IHC-P
Host or Source
Rabbit
Preservative
1 mg/ml in 1X PBS; rAlbumin free, sodium azide free
Isotype
Rabbit IgG, kappa

UniProtKB · P01880

Immunoglobulin heavy constant delta

IGHD_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P01880
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
IGHD
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
A0A087WUS7, Q6P4I8, Q8WU38
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Biological process

Adaptive immunityImmunity

Coding sequence diversity

Alternative splicing

Cellular component

Cell membraneImmunoglobulinMembraneSecreted

PTM

Disulfide bondGlycoprotein

Domain

Immunoglobulin domainTransmembraneTransmembrane helix

Related Products

CatalogName
GTR18306123Human IgD heavy chain Antibody
GTR18305993Mouse IgD heavy chain Antibody
GTR18306122Human IgD heavy chain Antibody
GTR18305992Mouse IgD heavy chain Antibody
GTR18305743Rat IgD heavy chain Antibody
GTR18305742Rat IgD heavy chain Antibody
GTR18306121Human IgD heavy chain Antibody
GTR18306000Mouse IgD heavy chain Antibody
GTR18305999Mouse IgD heavy chain Antibody
GTR18305998Mouse IgD heavy chain Antibody

Alternative Products

CatalogName
GWB-CD860FClathrin Heavy chain Antibody
GWB-Q00099IgG Heavy Chain Antibody
DF4828-01Ferritin Heavy Chain Antibody
V2144-100UGIgM Heavy Chain Antibody
V4322SAF-100UGIgD Antibody / Heavy chain
ABD7705Ferritin Heavy Chain Antibody
abx022414Prekallikrein Heavy Chain Antibody
abx140244Kinesin (heavy chain) Antibody
abx411951Kinesin Heavy Chain Antibody
GWB-7BF110Dynein Heavy chain Antibody

Popular Products