SLX-4090

• Description:

  SLX-4090 is an orally active enterocytic-specific microsomal triglyceride transfer protein (MTP) inhibitor with an IC50 of 8.0 nM. SLX-4090 can be used for the research of dyslipidemia[1].

• UNSPSC:

  12352005

• Target:

  Microsomal Triglyceride Transfer Protein (MTP)

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Metabolism-sugar/lipid metabolism

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/slx-4090.html

• Purity:

  98.97

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  O=C(N1CC2=C(C=C(NC(C3=CC=CC(OC)=C3C4=CC=C(C(F)(F)F)C=C4)=O)C=C2)CC1)OC5=CC=CC=C5

• Molecular Formula:

  C31H25F3N2O4

• Molecular Weight:

  546.54

• References & Citations:

  [1]Enoch Kim, et al. A small-molecule inhibitor of enterocytic microsomal triglyceride transfer protein, SLx-4090: biochemical, pharmacodynamic, pharmacokinetic, and safety profile. J Pharmacol Exp Ther. 2011 Jun;337 (3) :775-85.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, protect from light)

• Scientific Category:

  Reference compound1

• Clinical Information:

  Phase 2

• CAS Number:

  [913541-47-6]