26-Deoxyactein

CAT: 0804-HY-N6264-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-N6264-01Size:1 mg
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Description
26-Deoxyactein is a constituent isolated from Cimicifuga racemosa, prevents TCDD-induced osteoblasts damage. 26-Deoxyactein inhibits increased AhR, CYP1A1 and ERK levels[1].
CAS Number
[264624-38-6]
UNSPSC
12352005
Target
Aryl Hydrocarbon Receptor; ERK
Type
Natural Products
Related Pathways
Immunology/Inflammation; MAPK/ERK Pathway; Stem Cell/Wnt
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/27-deoxyactein.html
Purity
99.76
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
C[C@]12[C@@]3([H])[C@@]4(C[C@H]([C@@]1([C@]5([H])[C@](O[C@]6([C@@]7([H])[C@](O7)(CO6)C)C[C@H]5C)([H])C2)C)OC(C)=O)[C@@]8([C@](CC3)([H])C(C)([C@H](CC8)O[C@H]9[C@@H]([C@H]([C@@H](CO9)O)O)O)C)C4
Molecular Formula
C37H56O10
Molecular Weight
660.83
References & Citations
[1]Suh KS, et al. 27-Deoxyactein prevents 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced cellular damage in MC3T3-E1 osteoblastic cells. J Environ Sci Health A Tox Hazard Subst Environ Eng. 2018 May 12;53 (6) :561-570.|[2]Chen SN, et al. Isolation, structure elucidation, and absolute configuration of 26-deoxyactein from Cimicifuga racemosa and clarification of nomenclature associated with 27-deoxyactein. J Nat Prod. 2002;65 (4) :601-605.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported

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