Tos-PEG2-O-Propargyl
CAT:
804-HY-130162-02
Size:
250 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Tos-PEG2-O-Propargyl
- CAS Number: 1119249-30-7
- UNSPSC Description: Tos-PEG2-O-Propargyl is a PEG-based PROTAC linker can be used in the synthesis of Thalidomide-O-PEG2-propargyl (HY-126458)[1]. Tos-PEG2-O-Propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
- Target Antigen: PROTAC Linkers
- Type: Reference compound
- Related Pathways: PROTAC
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/tos-peg2-o-propargyl.html
- Purity: 98.47
- Solubility: Ethanol : 50 mg/mL (ultrasonic)
- Smiles: C#CCOCCOCCOS(C1=CC=C(C)C=C1)(=O)=O
- Molecular Weight: 298.36
- References & Citations: [1]Wurz RP, et al. A "Click Chemistry Platform" for the Rapid Synthesis of Bispecific Molecules for Inducing Protein Degradation. J Med Chem. 2018 Jan 25;61(2):453-461.
- Shipping Conditions: Room Temperature
- Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
- Clinical Information: No Development Reported