nNOS-IN-1

nNOS-IN-1

• CAS Number: 945762-00-5
• UNSPSC Description: nNOS-IN-1(Compound 14) is an inhibitor for nitric oxide synthases (NOS), that exhibits inhibitory activities against neuroal, inducible and endothelial NOS, with IC50s of 2.5, 5.7 and 13 μM, respectively[1].
• Target Antigen: NO Synthase
• Type: Reference compound
• Related Pathways: Immunology/Inflammation
• Applications: Neuroscience-Neuromodulation
• Field of Research: Neurological Disease; Cardiovascular Disease
• Assay Protocol: https://www.medchemexpress.com/nnos-in-1.html
• Purity: 99.53
• Solubility: DMSO : 100 mg/mL (ultrasonic)
• Smiles: N#CC1=CC=CC2=C1NN=C2Br
• Molecular Weight: 222.04
• References & Citations: [1]Cottyn B, et al., Inhibitory effects of a series of 7-substituted-indazoles toward nitric oxide synthases: particular potency of 1H-indazole-7-carbonitrile. Bioorg Med Chem. 2008 Jun 1;16(11):5962-73.
• Shipping Conditions: Room Temperature
• Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
• Clinical Information: No Development Reported