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Pro8-Oxytocin (TFA)

CAT: 0804-HY-P4990A-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-P4990A-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Pro8-Oxytocin TFA is a a modified oxytocin (OXT) ligand. Pro8-Oxytocin produces more potent and efficacious responses at primate OXTR and stronger behavioral effects than the consensus mammalian OXT ligand (Leu8-Oxytocin). Pro8-Oxytocin TFA produce a less efficacious response than Vasopressin (AVP) at human AVPR1a and higher efficacious response than AVP at marmoset AVPR1a[1].
UNSPSC
12352209
Target
Oxytocin Receptor
Type
Peptides
Related Pathways
GPCR/G Protein
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Endocrinology
Assay Protocol
https://www.medchemexpress.com/pro8-oxytocin-tfa.html
Purity
99.68
Solubility
10 mM in DMSO
Smiles
O=C(N1[C@@H](CCC1)C(NCC(N)=O)=O)[C@H]2N(CCC2)C([C@H]3NC([C@@H](NC([C@@H](NC([C@](NC([C@@H](NC([C@H](CSSC3)N)=O)CC4=CC=C(C=C4)O)=O)([H])[C@@H](C)CC)=O)CCC(N)=O)=O)CC(N)=O)=O)=O.OC(C(F)(F)F)=O.[x]
Molecular Formula
C42H62N12O12S2.xC2HF3O2
References & Citations
[1]Mustoe A, et al. Leu8 and Pro8 oxytocin agonism differs across human, macaque, and marmoset vasopressin 1a receptors. Sci Rep. 2019 Oct 29;9 (1) :15480.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported

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