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[KO Validated] DNMT3A polyclonal antibody

CAT: 0013-GTR18309951-02Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0013-GTR18309951-02Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
[KO Validated] DNMT3A polyclonal antibody
Product Name Alternative
DNMT3A; DNMT3A2; M.HsaIIIA; TBRS; DNMT3A
UniProt
Q9Y6K1
Reactivity
Human, Rat
Immunogen
A synthetic peptide of human DNMT3A (NP_072046.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Epigenetics & Chromatin
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration
1mg/ml
Dilution
WB,1:500 - 1:2000
Form
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH 7.2
Molecular Weight
140kDa
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
WB
Host or Source
Rabbit

UniProtKB · Q9Y6K1

DNA (cytosine-5)-methyltransferase 3A

DNM3A_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9Y6K1
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
DNMT3A
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
Dnmt3a
EC number
2.1.1.37
Processing
—
Secondary accessions
E9PEB8, Q86TE8, Q86XF5, Q8IZV0, Q8WXU9
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative promoter usageAlternative splicing

Molecular function

Chromatin regulatorDNA-bindingMethyltransferaseRepressorTransferase

Cellular component

ChromosomeCytoplasmNucleus

Disease

Disease variantDwarfismIntellectual disability

PTM

Isopeptide bondMethylationPhosphoproteinUbl conjugation

Ligand

Metal-bindingS-adenosyl-L-methionineZinc

Domain

Zinc-finger

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