[KO Validated] DNMT3A Rabbit mAb (AMR13011N)

• Background:

  CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated. [provided by RefSeq, Mar 2016]

• Synonyms:

  DNMT3A; DNMT3A2; M.HsaIIIA; TBRS; DNMT3A

• Gene ID:

  1788

• UniProt:

  Q9Y6K1

• Cellular Locus:

  Cytoplasm, Nucleus

• Applications:

  WB (Mus musculus)

• Dilution:

  WB 1:500 - 1:2000 IP 1:50 - 1:200

• Form:

  Liquid

• Buffer:

  Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.

• Molecular Weight:

  Calculated MW: 130kDa Observed MW: 80KDa/140KDa

• Storage Conditions:

  Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

• Overview:

  We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality [KO Validated] DNMT3A Rabbit mAb (AMR13011N) .

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=1788

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q9Y6K1

• AA Sequence:

  Email for sequence