nSMase2-IN-1
CAT:
804-HY-155111-02
Size:
10 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
nSMase2-IN-1
- CAS Number: 2968322-24-7
- UNSPSC Description: nSMase2-IN-1 is an orally active Neutral sphingomyelinase 2 (nSMase2) inhibitor with an IC50 value of 0.13 ± 0.06 μM. nSMase2-IN-1 is metabolically stable in liver microsomes and orally available with a favorable brain-to-plasma ratio. nSMase2-IN-1 can be used for nervous system disease research[1].
- Target Antigen: Phospholipase
- Type: Reference compound
- Related Pathways: Metabolic Enzyme/Protease
- Applications: Neuroscience-Neuromodulation
- Field of Research: Neurological Disease
- Assay Protocol: https://www.medchemexpress.com/nsmase2-in-1.html
- Solubility: 10 mM in DMSO
- Smiles: CN(C1=C2N(C=CC(N3CCOCC3)=N2)N=C1)C
- Molecular Weight: 247.30
- References & Citations: [1]Novotna K, et al. Neutral sphingomyelinase 2 inhibitors based on the pyrazolo[1,5-a]pyrimidin-3-amine scaffold. Eur J Med Chem. 2023 Nov 5;259:115674.
- Shipping Conditions: Room Temperature
- Clinical Information: No Development Reported