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Lamin A + C Rabbit Polyclonal Antibody

CAT: 0013-GTR18308228Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0013-GTR18308228Size:100 µL
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Description
Lamin A + C Rabbit Polyclonal Antibody
Product Name Alternative
Lamin A/C , CDCD1 , CDDC , CMD1A , CMT2B1 , EMD2 , FPL , FPLD , FPLD2 , HGPS , IDC , LDP1 , LFP , LGMD1B , LMN1 , LMNC , LMNL1 , MADA , PRO1
UniProt
P02545
Reactivity
Human, Mouse
Immunogen
Recombinant protein encompassing a sequence within the center region of human Lamin A + C. The exact sequence is proprietary.
Target
Lamin A/C
Clonality
Polyclonal
Conjugation
Unconjugated
Purification
Purified by antigen-affinity chromatography.
Concentration
0.27 mg/ml (Please refer to the vial label for the specific concentration.)
Dilution
WB: 1:500-1:10000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:66-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Form
Liquid
Molecular Weight
74
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
Positive control: C2C12 , NIH-3T3 , HeLa
Tested Applications
ICC, IHC-P, IP, WB
Host or Source
Rabbit
Preservative
0.1M Tris, 0.1M Glycine, 20% Glycerol, 0.01% Thimerosal.
Isotype
IgG

UniProtKB · P02545

Prelamin-A/C

LMNA_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P02545
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
LMNA
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
B4DI32, D3DVB0, D6RAQ3, E7EUI9, P02546, Q5I6Y4, Q5I6Y6, Q5TCJ2, Q5TCJ3, Q6UYC3, Q969I8, Q96JA2
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationGlycoproteinIsopeptide bondLipoproteinMethylationPhosphoproteinPrenylationUbl conjugation

Coding sequence diversity

Alternative splicing

Disease

CardiomyopathyCharcot-Marie-Tooth diseaseCongenital muscular dystrophyDisease variantEmery-Dreifuss muscular dystrophyLimb-girdle muscular dystrophyNeurodegenerationNeuropathy

Domain

Coiled coil

Cellular component

Intermediate filamentNucleus

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