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Rabbit Lamin-A/C Antibody

CAT: 0013-GTR18218035-01Size: 10 µLDry Ice: NoHazardous: No
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CAT#:0013-GTR18218035-01Size:10 µL
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Description
Lamin-A/C Antibody
Product Name Alternative
70 kDa lamin; CDCD1; CDDC; CMD1A; CMT2B1; EMD2; epididymis secretory sperm binding protein; FPL; FPLD; FPLD2; HGPS; IDC; lamin; lamin A/C-like 1; LDP1; LFP; LGMD1B; LMN1; LMNC; LMNL1; MADA; mandibuloacral dysplasia type A; prelamin-A/C; PRO1; renal carcinoma antigen NY-REN-32
UniProt
P02545
Reactivity
Human, Mouse
Immunogen
Between 1 and 50
Target
Lamin-A/C
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Cardiovascular Research, Neuroscience
Purification
Antigen Affinity Purified
Concentration
200 μg/ml
Dilution
WB - 1:2,000 - 1:10,000; IP - 2 - 10 μg/mg lysate; IHC - 1:200 - 1:1,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.; ICC-IF - 1:100 - 1:500. Formaldehyde fixation is recommended. Permeabilization with Triton-X 100 is recommended for formaldehyde-fixed cells.
Form
Liquid
Storage Conditions
2 - 8°C
Notes
For research use only.
Applications Notes
Format: Whole IgG
Prediction Reactivity
Porcine
Tested Applications
ICC, IHC, IP, WB
NCBI Accession Number
NP_005563.1
Host or Source
Rabbit
Preservative
Tris-buffered Saline containing 0.1% rAlbumin and 0.09% Sodium Azide
Isotype
IgG

UniProtKB · P02545

Prelamin-A/C

LMNA_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P02545
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
LMNA
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
B4DI32, D3DVB0, D6RAQ3, E7EUI9, P02546, Q5I6Y4, Q5I6Y6, Q5TCJ2, Q5TCJ3, Q6UYC3, Q969I8, Q96JA2
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationGlycoproteinIsopeptide bondLipoproteinMethylationPhosphoproteinPrenylationUbl conjugation

Coding sequence diversity

Alternative splicing

Disease

CardiomyopathyCharcot-Marie-Tooth diseaseCongenital muscular dystrophyDisease variantEmery-Dreifuss muscular dystrophyLimb-girdle muscular dystrophyNeurodegenerationNeuropathy

Domain

Coiled coil

Cellular component

Intermediate filamentNucleus

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