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UCSF924

CAT: 0804-HY-125751-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-125751-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
UCSF924, a chemical probe, is a potent and specific dopamine D4 receptor (DRD4) partial agonist with a EC50 of 4.2 nM. UCSF924 has no off-target effects on more than 320 non-olfactory GPCRs. UCSF924 can be used for research in the field of neuropsychiatric diseases[1][2].
CAS Number
1434515-70-4
UNSPSC
12352005
Target
Dopamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ucsf924.html
Purity
99.53
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
OC1=CC(CNCCCOC2=CC=CC=C2)=NC3=CC=C(C)C=C13
Molecular Formula
C20H22N2O2
Molecular Weight
322.40
References & Citations
[1]Wang S, et al. D4 dopamine receptor high-resolution structures enable the discovery of selective agonists. Science. 2017 Oct 20;358 (6361) :381-386.|[2]Thomas G E. Characterizing antipsychotic behavioral and corticostriatal neurophysiological effects to psychotomimetic challenge. Duke University, 2022.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
D4 Receptor

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