S100 rabbit pAb

S100 rabbit pAb

• Description: S100 calcium binding protein A1 (S100A1) Homo sapiens The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-induced Ca2+ release, inhibition of microtubule assembly, and inhibition of protein kinase C-mediated phosphorylation. Reduced expression of this protein has been implicated in cardiomyopathies. [provided by RefSeq, Jul 2008],
• Synonyms: Protein S100-A1 (S-100 protein alpha chain;S-100 protein subunit alpha;S100 calcium-binding protein A1)
• Gene ID: 6271
• UniProt: P23297
• Cellular Locus: Cytoplasm. Sarcoplasmic reticulum. Mitochondrion.
• Host: Rabbit
• Species Reactivity: Human, Rat, Mouse
• Immunogen: Recombinant Protein of S100
• Clonality: Polyclonal
• Validated Applications: WB, IHC, IF
• Stability: 1 year
• Concentration: 1 mg/mL
• Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
• Molecular Weight: 15kD
• Storage Conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.