Products for Research Use Only
RegisterLogin

Simridarlimab

CAT: 0804-HY-P99903-01Size: 1 mgDry Ice: YesHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-P99903-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Simridarlimab (IBI-322) is a bispecific antibody targeting PD-L1 and CD47. Simridarlimab attenuates CD47 activity in monovalent binding and blockes PD-L1 activity in bivalent binding. Simridarlimab selectively binds to CD47+PD-L1+ tumor cells, effectively inhibits CD47-SIRPα signal and triggered strong tumor cell phagocytosis in vitro[1].
CAS Number
2378862-90-7
Product Name Alternative
IBI-322
UNSPSC
12352203
Target
CD47; PD-1/PD-L1
Type
Inhibitory Antibodies
Related Pathways
Immunology/Inflammation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/simridarlimab.html
Purity
99.81
Solubility
10 mM in DMSO
Smiles
[Simridarlimab]
Molecular Weight
(125.734 kDa)
References & Citations
[1]CD47/PD-L1 bispecific antibody for enhanced anti-tumor activity and limited toxicity. Cancer Immunol Immunother. 2021 Feb;70 (2) :365-376.
Shipping Conditions
Dry Ice
Storage Conditions
Store at -80°C for 2 years
Scientific Category
Inhibitory Antibodies
Clinical Information
No Development Reported

Alternative Products

CatalogName
T81155-01Simridarlimab
GTR18333550-01Simridarlimab Antibody
MBS1563796-01Research Grade Simridarlimab
E55B1280Simridarlimab (Reference antibody)
GTR18697321-01Simridarlimab Human Monoclonal Antibody
PX-TA1753-01Simridarlimab Biosimilar - Anti-PDL1 & MER6 mAb - Research Grade
A135523Simridarlimab Biosimilar (Monoclonal, (G1_L-kappa) _VH-VH-h-CH2-CH3)

Popular Products