C12-113

• Description:

  C12-113 is a lipidoid delivery agent that can be used to transfect siRNA into cells. C12-113 can also be combined with other lipids to form lipid nanoparticles (LNPs) for the delivery of mRNA encoding the spike glycoprotein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in mice[1][2].

• UNSPSC:

  12352200

• Hazard Statement:

  H302, H315, H319, H335

• Target:

  Liposome

• Type:

  Biochemical Assay Reagents

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  COVID-19-anti-virus

• Field of Research:

  Infection; Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/c12-113.html

• Concentration:

  29.26 mM * 40 μL in Ethanol

• Purity:

  98.6

• Solubility:

  10 mM in DMSO

• Smiles:

  OC(CCCCCCCCCC)CN(CC(CCCCCCCCCC)O)CCN(CCN(CC(CCCCCCCCCC)O)CC(CCCCCCCCCC)O)C

• Molecular Formula:

  C53H111N3O4

• Molecular Weight:

  854.47

• Precautions:

  H302, H315, H319, H335

• References & Citations:

  [1]Li J, Song J S, et al. YY1 regulates melanocyte development and function by cooperating with MITF[J]. PLoS genetics, 2012, 8 (5) : e1002688.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Solution, -20°C, 2 years

• Scientific Category:

  Biochemical Assay Reagents

• Clinical Information:

  No Development Reported

• CAS Number:

  1220890-27-6