Quinine (sulfate)
CAT:
804-HY-B1751B-02
Size:
100 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Quinine (sulfate)
- CAS Number: 549-56-4
- UNSPSC Description: Quinidine sulfate is an antiarrhythmic agent. Quinidine sulfate is a potent, orally active, selective cytochrome P450db inhibitor. Quinidine sulfate is also a K+ channel blocker with an IC50 of 19.9 μM. Quinidine sulfate can be used for malaria research[1][2][3].
- Target Antigen: Cytochrome P450; Parasite; Potassium Channel
- Type: Reference compound
- Related Pathways: Anti-infection;Membrane Transporter/Ion Channel;Metabolic Enzyme/Protease
- Applications: COVID-19-immunoregulation
- Field of Research: Cancer; Infection; Cardiovascular Disease
- Assay Protocol: https://www.medchemexpress.com/quinine-sulfate.html
- Purity: 97.0
- Solubility: 10 mM in DMSO
- Smiles: O[C@H](C1=CC=NC2=C1C=C(OC)C=C2)[C@@]3([H])[N@](C[C@@H]4C=C)CC[C@H]4C3.O=S(O)(O)=O
- Molecular Weight: 422.50
- References & Citations: [1]Kehl SJ, et al. Quinidine-induced inhibition of the fast transient outward K+ current in rat melanotrophs. Br J Pharmacol. 1991 Jul;103(3):1807-13.|[2]Roden DM, et al. Class I antiarrhythmic agents: quinidine, procainamide and N-acetylprocainamide, disopyramide.|[3]Moody DE, et al. Quinidine inhibits in vivo metabolism of amphetamine in rats: impact upon correlation between GC/MS and immunoassay findings in rat urine. J Anal Toxicol. 1990 Sep-Oct;14(5):311-7.
- Shipping Conditions: Room Temperature
- Storage Conditions: 4°C (Powder, protect from light, stored under nitrogen)
- Clinical Information: Launched