Z-Phe-Tyr(tBu)-diazomethylketone

CAT:

804-HY-138208-05

Size:

1 mg

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CAS Number: 114014-15-2
UNSPSC Description: Z-Phe-Tyr(tBu)-diazomethylketone is a potent cathepsin L inhibitor. Z-Phe-Tyr(tBu)-diazomethylketone mediates reovirus disassembly. Z-Phe-Tyr(tBu)-diazomethylketone decreases viral detection[1][2].
Target Antigen: Cathepsin; SARS-CoV
Type: Reference compound
Related Pathways: Anti-infection;Metabolic Enzyme/Protease
Field of Research: Infection
Assay Protocol: https://www.medchemexpress.com/z-phe-tyr-tbu-diazomethylketone.html
Smiles: O=C(N[C@H](C(C=[N+]=[N-])=O)CC(C=C1)=CC=C1OC(C)(C)C)[C@@H](NC(OCC2=CC=CC=C2)=O)CC3=CC=CC=C3
Molecular Weight: 542.63
References & Citations: [1]Ebert DH, et al. Cathepsin L and cathepsin B mediate reovirus disassembly in murine fibroblast cells. J Biol Chem. 2002 Jul 5;277(27):24609-17.|[2]Perez-Bermejo JA, et al. SARS-CoV-2 infection of human iPSC-derived cardiac cells reflects cytopathic features in hearts of patients with COVID-19. Sci Transl Med. 2021 Apr 21;13(590):eabf7872.
Shipping Conditions: Blue Ice

Cat	Name
HY-138208-07	Z-Phe-Tyr(tBu)-diazomethylketone
HY-138208-06	Z-Phe-Tyr(tBu)-diazomethylketone
HY-138208-05	Z-Phe-Tyr(tBu)-diazomethylketone
HY-138208-03	Z-Phe-Tyr(tBu)-diazomethylketone
HY-138208-02	Z-Phe-Tyr(tBu)-diazomethylketone
HY-138208-04	Z-Phe-Tyr(tBu)-diazomethylketone
HY-138208-01	Z-Phe-Tyr(tBu)-diazomethylketone
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HY-P4295-05	Z-Phe-Ala-diazomethylketone
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