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Z-Phe-Tyr(tBu)-diazomethylketone

CAT:
804-HY-138208-04
Size:
10 mg
Price:
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  • Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
  • Dry Ice Shipment: No
Z-Phe-Tyr(tBu)-diazomethylketone - image 1

Z-Phe-Tyr(tBu)-diazomethylketone

  • CAS Number: 114014-15-2
  • UNSPSC Description: Z-Phe-Tyr(tBu)-diazomethylketone is a potent cathepsin L inhibitor. Z-Phe-Tyr(tBu)-diazomethylketone mediates reovirus disassembly. Z-Phe-Tyr(tBu)-diazomethylketone decreases viral detection[1][2].
  • Target Antigen: Cathepsin; SARS-CoV
  • Type: Reference compound
  • Related Pathways: Anti-infection;Metabolic Enzyme/Protease
  • Field of Research: Infection
  • Assay Protocol: https://www.medchemexpress.com/z-phe-tyr-tbu-diazomethylketone.html
  • Smiles: O=C(N[C@H](C(C=[N+]=[N-])=O)CC(C=C1)=CC=C1OC(C)(C)C)[C@@H](NC(OCC2=CC=CC=C2)=O)CC3=CC=CC=C3
  • Molecular Weight: 542.63
  • References & Citations: [1]Ebert DH, et al. Cathepsin L and cathepsin B mediate reovirus disassembly in murine fibroblast cells. J Biol Chem. 2002 Jul 5;277(27):24609-17.|[2]Perez-Bermejo JA, et al. SARS-CoV-2 infection of human iPSC-derived cardiac cells reflects cytopathic features in hearts of patients with COVID-19. Sci Transl Med. 2021 Apr 21;13(590):eabf7872.
  • Shipping Conditions: Blue Ice