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Terrecyclic Acid

CAT: 0804-HY-137936Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-137936Size:1 Each
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Description
Terrecyclic acid is a sesquiterpene originally isolated from A. terreus with antibiotic and anticancer activity. It is active against S. aureus, B. subtilis, and M. roseus (MICs=25, 50, and 25 μg/mL, respectively) . Terrecyclic acid induces a heat shock response, increases levels of reactive oxygen species (ROS), and inhibits NF-κB activity and cell growth in 3T3-Y9-B12 cells.2 In vivo, terrecyclic acid (0.1, 1, and 10 mg/ml) reduces the number of ascitic fluid tumor cells in a mouse model of P388 murine leukemia.
CAS Number
83058-94-0
UNSPSC
12352211
Target
Antibiotic
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/terrecyclic-acid.html
Smiles
OC([C@H](CC1)[C@@](C2)(C3=C)[C@@](CC3=O)([H])[C@]1([H])C2(C)C)=O
Molecular Formula
C15H20O3
Molecular Weight
248.32
References & Citations
[1]Nakagawa, et al. Terrecyclic acid A, a new antibiotic from Aspergillus terreus. I. Taxonomy, production, and chemical and biological properties. J. Antibiot. (Tokyo) 35 (7), 778-782 (1982) .
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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