Boc-NHCH2-Ph-pyrimidine-NH2

Boc-NHCH2-Ph-pyrimidine-NH2

• CAS Number: 3040121-15-8
• UNSPSC Description: Boc-NHCH2-Ph-pyrimidine-NH2 is the linker for PROTAC molecule XYD198 (HY-161498)[1].
• Target Antigen: PROTAC Linkers
• Type: Reference compound
• Related Pathways: PROTAC
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/boc-nhch2-ph-pyrimidine-nh2.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(OC(C)(C)C)NCC(C=C1)=CC=C1C2=NC=C(N)C=N2
• Molecular Weight: 300.36
• References & Citations: [1]Hu J, et al., Discovery of Highly Potent and Efficient CBP/p300 Degraders with Strong In Vivo Antitumor Activity. J Med Chem. 2024 May 9;67(9):6952-6986.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported