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PIK-108

CAT: 0804-HY-111184-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-111184-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PIK-108 is a non-ATP competitive, allosteric p110β/p110δ selective inhibitor[1].
CAS Number
901398-68-3
UNSPSC
12352005
Target
PI3K
Type
Reference compound
Related Pathways
PI3K/Akt/mTOR
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pik-108.html
Purity
99.05
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C1C=C(N2CCOCC2)OC3=C(C(NC4=CC=CC=C4)C)C=C(C)C=C13
Molecular Formula
C22H24N2O3
Molecular Weight
364.44
References & Citations
[1]Zachary A Knight, et al. A pharmacological map of the PI3-K family defines a role for p110alpha in insulin signaling. Cell. 2006 May 19;125 (4) :733-47.|[2]Jack S Chen, et al. Characterization of structurally distinct, isoform-selective phosphoinositide 3'-kinase inhibitors in combination with radiation in the treatment of glioblastoma. Mol Cancer Ther. 2008 Apr;7 (4) :841-50.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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