Products for Research Use Only
RegisterLogin

EML 425

CAT: 0804-HY-110263-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-110263-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
EML425 is a potent and selective CREB binding protein (CBP) /p300 inhibitor with IC50s of 2.9 and 1.1 μM, respectively.
CAS Number
1675821-32-5
UNSPSC
12352005
Target
Epigenetic Reader Domain; Histone Acetyltransferase
Type
Reference compound
Related Pathways
Epigenetics
Applications
Neuroscience-Neuromodulation
Field of Research
Metabolic Disease; Neurological Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/EML_425.html
Concentration
10mM
Purity
98.04
Solubility
DMSO : ≥ 250 mg/mL
Smiles
O=C(N(C(N(CC1=CC=CC=C1)C/2=O)=O)CC3=CC=CC=C3)C2=C/C4=C(C=C(O)C=C4C)C
Molecular Formula
C27H24N2O4
Molecular Weight
440.49
References & Citations
[1]Milite C, et al. A novel cell-permeable, selective, and noncompetitive inhibitor of KAT3 histone acetyltransferases from a combined molecular pruning/classical isosterism approach. J Med Chem. 2015 Mar 26;58 (6) :2779-98.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CBP/p300; TIP60

Related Products

CatalogName
HY-W726893ATTO 425
HY-124756-01SBI-425
HY-D1926ATTO 425 streptavidin
HY-D1928ATTO 425 amine
HY-D1930ATTO 425 azide
HY-W952952CRBN ligand-425
HY-D1925ATTO 425 maleimide
HY-D1927ATTO 425 biotin
HY-153524-01ATTO 425 NHS ester
HY-D1802-01Vari Fluor 425 SE

Alternative Products

CatalogName
CN-A038-500GMAgar, Micropropagation - Type I (Gracilaria)
M2302-20HPhaseShield™ Gel Tubes, Heavy (200x 2ml)
M2302-20LPhaseShield™ Gel Tubes, Light (200x 2ml)
E-EL-M0380ELISA kit for Mouse CDKN1B (Cyclin Dependent Kinase Inhibitor 1B)
E-KAB-0415Human CA9 Antibody Pair Set
E-KAB-0614Porcine IL-2 Antibody Pair Set
PKSH030904Recombinant Human Purine nucleoside phosphorylase/PNP Protein (His Tag)
E-EL-P0403ELISA kit for Porcine MUC3 (Mucin 3)
E-EL-H2307ELISA kit for Human TL1A (Tumor Necrosis Factor Related Ligand 1A)
PKSH031652Recombinant Human IFNAR2/IFNABR Protein (Fc Tag)

Popular Products