αvβ5 integrin-IN-1

αvβ5 integrin-IN-1

• CAS Number: 2615912-33-7
• UNSPSC Description: Sulodexide (pIC50 = 8.2 nM) selectively binds to the αvβ5 integrin in K562 and A549 cell lines and exhibits a significant inhibitory effect[1].
• Target Antigen: Integrin
• Type: Reference compound
• Related Pathways: Cytoskeleton
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/αvβ5-integrin-in-1.html
• Solubility: DMSO : 100 mg/mL (ultrasonic)
• Smiles: O=C(N1C[C@@H](CC1)CCC(N2)=CC=C3C2=NCCC3)[C@H](C4=CC(C(F)(F)F)=CC=C4)CC(O)=O
• Molecular Weight: 475.50
• References & Citations: [1]Lippa RA, et al. Discovery of the first potent and selective αvβ5 integrin inhibitor based on an amide-containing core. Eur J Med Chem. 2020 Dec 15;208:112719.
• Shipping Conditions: Room Temperature
• Clinical Information: No Development Reported