3,7-DMF

3,7-DMF

• CAS Number: 20950-52-1
• UNSPSC Description: 3,7-DMF is an orally active inhibitor of TGF-β1-induced activation of HSCs. 3,7-DMF induces antioxidant genes and quenches ROS away, which can be used to study liver fibrosis[1].
• Target Antigen: TGF-beta/Smad
• Type: Reference compound
• Related Pathways: Stem Cell/Wnt;TGF-beta/Smad
• Applications: Cancer-Kinase/protease
• Field of Research: Others
• Assay Protocol: https://www.medchemexpress.com/3-7-dmf.html
• Solubility: 10 mM in DMSO
• Smiles: O=C1C(OC)=C(C2=CC=CC=C2)OC3=C1C=CC(OC)=C3
• Molecular Weight: 282.29
• References & Citations: [1]Hyomin Park , et al. Discovery of 3,7-dimethoxyflavone that inhibits liver fibrosis based on dual mechanisms of antioxidant and inhibitor of activated hepatic stellate cell. Free Radic Biol Med.2023, 204.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported