Chromogranin A Recombinant Mouse Monoclonal Antibody [D11-2-R]

Chromogranin A Recombinant Mouse Monoclonal Antibody [D11-2-R]

• Description: Chromogranin A or parathyroid secretory protein 1 (gene name CHGA) is a member of the granin family of neuroendocrine secretory proteins. As such, it is located in secretory vesicles of neurons and endocrine cells such as islet beta cell secretory granules in the pancreas. In humans, chromogranin A protein is encoded by the CHGA gene. Chromogranin A is the precursor to several functional peptides including vasostatin-1, vasostatin-2, pancreastatin, catestatin and parastatin. These peptides negatively modulate the neuroendocrine function of the releasing cell (autocrine) or nearby cells (paracrine). Chromogranin A induces and promotes the generation of secretory granules such as those containing insulin in pancreatic islet beta cells.
• Product Name Alternative: beta Granin antibody betagranin (N-terminal fragment of chromogranin A) antibody catestatin antibody CgA antibody CHG A antibody Chga antibody chromofungin antibody Chromogranin A antibody Chromogranin A parathyroid secretory protein 1 antibody Chromogranin A precursor antibody ChromograninA antibody CMGA_HUMAN antibody ER-37 antibody Pancreastatin antibody Parastatin antibody Parathyroid secretory protein 1 antibody Pituitary secretory protein I antibody Secretory protein I antibody SP I antibody SP-I antibody SP1 antibody SPI antibody Vasostatin antibody Vasostatin I antibody Vasostatin II antibody
• Abbreviation: CgA, SP-I, CHGA
• CAS Number: 9000-83-3
• Swiss Prot: P10645 Human, P26339 Mouse, P10354 Rat
• Cellular Locus: Secreted. Secretory vesicle lumen.
• Host: Mouse
• Species Reactivity: Human, Mouse, Rat
• Immunogen: Synthetic peptide within human Chromogranin-A aa 415-457/457.
• Isotype: IgG1
• Clone: D11-2-R
• Conjugation: Non-conjugated
• Type: Recombinant Mouse monoclonal Antibody
• Applications: IHC-P
• Positive Control: Human atypical carcinoid tissue, human pancreas tissue, mouse pancreas tissue, rat pancreas tissue.
• Concentration: 1 mg/mL
• Dilution: IHC-P: 1:15,000
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 52 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
• Recombinant Antibody: Yes