PMPMEase-IN-1
CAT:
804-HY-118041
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
PMPMEase-IN-1
- CAS Number: 1190196-76-9
- UNSPSC Description: PMPMEase-IN-1 is an allylated methylated protein methylesterase inhibitor with the property of inhibiting PMPMEase activity. PMPMEase-IN-1 may provide a useful strategy for cancer inhibition by enhancing its affinity for polyisoprenyl derivatives. PMPMEase-IN-1 showed the potential to have an effective concentration (EC50) value in causing degeneration of human neuroblastoma SH-SY5Y cells. Specific inhibition of PMPMEase-IN-1 may help regulate the metabolism of polyisoprenyl proteins and thus maintain normal cell survival. Further development and application of PMPMEase-IN-1 may open up new avenues for inhibiting degenerative diseases and cancer[1].
- Target Antigen: Endogenous Metabolite
- Type: Reference compound
- Related Pathways: Metabolic Enzyme/Protease
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/pmpmease-in-1.html
- Smiles: O=S(CCSC/C=C(C)/CC/C=C(C)\C)(F)=O
- Molecular Weight: 280.42
- References & Citations: [1]Polyisoprenylation potentiates the inhibition of polyisoprenylated methylated protein methyl esterase and the cell degenerative effects of sulfonyl fluorides
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported