L-Norvaline

• Description:

  L-Norvaline is the inhibitor for arginase, that promotes the production of NO, reduces oxidative stress, improves insulin resistance, and exhibits antioxidant and anti-hyperglycemic effects. L-Norvaline can be used in research of Alzheimer’s disease[1][2].

• Product Name Alternative:

  Norvaline

• UNSPSC:

  12352211

• Hazard Statement:

  H302, H315, H319, H335

• Target:

  Amyloid-β; Arginase; TNF Receptor

• Type:

  Natural Products

• Related Pathways:

  Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; Neuronal Signaling

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Metabolic Disease; Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/l-norvaline.html

• Purity:

  98.0

• Solubility:

  DMSO : < 1 mg/mL (ultrasonic) |H2O : 50 mg/mL (ultrasonic)

• Smiles:

  N[C@@H](CCC)C(O)=O

• Molecular Formula:

  C5H11NO2

• Molecular Weight:

  117.15

• Precautions:

  H302, H315, H319, H335

• References & Citations:

  [1]Polis B, et al., L-Norvaline, a new therapeutic agent against Alzheimer's disease. Neural Regen Res. 2019 Sep;14 (9) :1562-1572.|[2]Javrushyan H, et al., Antihyperglycemic activity of L-norvaline and L-arginine in high-fat diet and streptozotocin-treated male rats. Exp Mol Pathol. 2022 Jun;126:104763.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  Store at room temperature 3 years

• Scientific Category:

  Natural Products

• Clinical Information:

  No Development Reported

• CAS Number:

  6600-40-4