DL-Norvaline

• Description:

  DL-Norvaline, a derivative of L-norvaline, L-norvaline is a non-competitive inhibitor of arginase.

• Product Name Alternative:

  2-Aminopentanoic acid

• UNSPSC:

  12352211

• Hazard Statement:

  H302, H315, H319, H335

• Target:

  Arginase; Endogenous Metabolite

• Type:

  Natural Products

• Related Pathways:

  Immunology/Inflammation; Metabolic Enzyme/Protease

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/DL-Norvaline.html

• Purity:

  98.0

• Solubility:

  10 mM in DMSO|H2O : 50 mg/mL (ultrasonic)

• Smiles:

  CCCC (N) C (O) =O

• Molecular Formula:

  C5H11NO2

• Molecular Weight:

  117.15

• Precautions:

  H302, H315, H319, H335

• References & Citations:

  [1]Sosroseno W, et al. Arginase activity in a murine macrophage cell line (RAW264.7) stimulated with lipopolysaccharide from Actinobacillus actinomycetemcomitans. Oral Microbiol Immunol. 2006 Jun;21 (3) :145-50.|[2]El-Bassossy HM, et al. Arginase inhibition alleviates hypertension associated with diabetes: effect on endothelial dependent relaxation and NO production. Vascul Pharmacol. 2012 Nov-Dec;57 (5-6) :194-200.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Natural Products

• Clinical Information:

  No Development Reported

• Isoform:

  Human Endogenous Metabolite

• CAS Number:

  760-78-1