DL-Norvaline

• Description :

  DL-Norvaline, a derivative of L-norvaline, L-norvaline is a non-competitive inhibitor of arginase.

• Product Name Alternative :

  2-Aminopentanoic acid

• UNSPSC :

  12352211

• Hazard Statement :

  H302, H315, H319, H335

• Target :

  Arginase; Endogenous Metabolite

• Type :

  Natural Products

• Related Pathways :

  Immunology/Inflammation; Metabolic Enzyme/Protease

• Applications :

  Metabolism-protein/nucleotide metabolism

• Field of Research :

  Metabolic Disease

• Assay Protocol :

  https://www.medchemexpress.com/DL-Norvaline.html

• Purity :

  98.0

• Solubility :

  10 mM in DMSO|H2O : 50 mg/mL (ultrasonic)

• Smiles :

  CCCC(N)C(O)=O

• Molecular Formula :

  C5H11NO2

• Molecular Weight :

  117.15

• Precautions :

  H302, H315, H319, H335

• References & Citations :

  [1]Sosroseno W, et al. Arginase activity in a murine macrophage cell line (RAW264.7) stimulated with lipopolysaccharide from Actinobacillus actinomycetemcomitans. Oral Microbiol Immunol. 2006 Jun;21 (3) :145-50.|[2]El-Bassossy HM, et al. Arginase inhibition alleviates hypertension associated with diabetes: effect on endothelial dependent relaxation and NO production. Vascul Pharmacol. 2012 Nov-Dec;57 (5-6) :194-200.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Natural Products

• Clinical Information :

  No Development Reported

• Isoform :

  Human Endogenous Metabolite

• CAS Number :

  [760-78-1]